The project investigates whether an oil rich in ketolic acid can reduce eczema and improve skin quality in people with atopic eczema—an alternative to current cortisone therapy.
Atopic eczema is a widespread skin condition caused by defects in the skin barrier, leading to dryness, wounds and infections. The disease significantly affects quality of life, and current treatment relies largely on cortisone-based preparations, which can have undesirable side effects such as thinning of the skin. There is therefore a need for new and gentler treatment options.
Lipids play a crucial role in both the skin’s barrier function and its signalling processes. In atopic eczema, lipid composition is altered, contributing to inflammation and a weakened barrier. Oil rich in ketolinic acid has shown anti‑inflammatory effects in other tissues and may increase levels of the omega‑3 fatty acids EPA and DHA, which also have anti‑inflammatory properties.
This project will investigate whether ketolinic‑acid‑rich oil can improve skin quality and reduce eczema severity in people with atopic eczema and dry skin. The findings may provide the basis for a new, gentler treatment approach that reduces the need for cortisone.
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